Precision Meets Innovation: Welcome to Cogent HPLC Columns
At MicroSolv, we understand that your chromatography results depend on the quality and performance of your HPLC columns. That’s why Cogent HPLC columns are engineered to deliver exceptional reproducibility, selectivity, and efficiency—across a wide range of applications and separation modes.
Whether you're working in pharmaceutical development, clinical research, environmental testing, or food safety, Cogent columns and our support offer the performance edge you need to stay ahead.
WHY CHOOSE A COGENT COLUMN?
Easy to use, strong technical support for lifetime of the column, great values.
Breakthrough TYPE-C™ Technology
Our flagship Cogent TYPE-C™ columns feature silica hydride particles—a proprietary advancement that enables unique selectivity, fast equilibration, and robust performance for both polar and non-polar analytes. These columns outperform traditional HILIC and reversed-phase options in many challenging separations.
Broad Application Versatility
Cogent columns support multiple separation modes:
Reversed Phase (RP)
Normal Phase (NP)
Ion Exchange (IEX)
HILIC
Aqueous Normal Phase (ANP)
This versatility and range allows you to optimize methods across diverse compound classes—from peptides and lipids to small molecules and charged species. It shows that our line was developed for new users to highly experienced chromatographers. From established methods, to scouting to research of unknown unknowns.
High Purity, High Consistency
Manufactured with ultra-pure silica and low metal content, Cogent columns deliver consistent peak shapes, low background noise, and reliable reproducibility—batch after batch.
Invest in this great column line with column lifetime support.
CHOOSING THE RIGHT COLUMN: Key Factors
Separation Mode
ANP: Ideal for polar compounds using reversed-phase solvents; excellent for LC-MS workflows.
RP: Best for non-polar or moderately polar compounds.
NP: Effective for polar analytes with polar stationary phases.
Ion Exchange: Designed for charged molecules and biomolecules.
Analyte Properties
Consider polarity, molecular weight, and charge to select the right stationary phase and pore size.
Column Specs
Particle Size: Smaller particles (e.g., 1.8μm) offer higher resolution.
Pore Size: Choose based on analyte size (e.g., 100Å for small molecules).
Dimensions: Length and diameter affect resolution and run time.
Application Needs
From high-throughput screening to sensitive trace analysis, Cogent offers tailored solutions to meet your performance goals.
Method Development Support
Our technical team provides expert guidance and method optimization resources to help you get the most from your column.
EXPLORE THE COGENT PRODUCT LINE
Cogent HPS™ – Base-deactivated columns (5μm) for traditional HPLC with excellent peak shapes.
Cogent IEX™ – Ion exchange columns for biological and polar compounds.
Cogent NP™ – Normal phase columns ideal for lipids, sugars, and preparative work.
Cogent RP™ – Premium reversed-phase columns with over 20 years of proven performance.
Cogent Similars™ – Cost-effective alternatives to leading USP legacy brands.
Cogent TYPE-C™ – Silica hydride columns offering unmatched selectivity for peptides, polar compounds, and closely related species.
READY TO OPTIMIZE YOUR SEPARATIONS?
Contact our technical team today to find the perfect Cogent column for your application.
Learn more about Cogent HPLC columns
Browse all Cogent columns by stationary phase
